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Effect of short follicular phase with follicular maturity on conception outcome

Catherine McDiarmid-Watt | Monday, March 24, 2008 | 0 comments

Photo by CatherineShort Follicular phase reduces fertility
Purpose: To determine if a short follicular phase despite attaining a mature follicle is associated with a lower pregnancy rate. Furthermore the study would determine if delaying the maturation of the follicle by the use of ethinyl estradiol could improve the pregnancy rate.

Methods: The clinical and viable pregnancy rates of 32 infertile patients were matched to 32 similar controls who ovulated at or past day 11. After 2-3 cycles of demonstrating ovulation before day 11 some patients were treated with ethinyl E[2], 20 mcg daily, from day 2 of the cycle until ovulation.


Results: Clinical and viable pregnancy rates for the normal ovulators (84.4%, 59.3%) were significantly higher than the rates for early ovulators (21.8%, 9.3%). However, the pregnancy rates were 83.3% and 66.7% for the subset of early ovulators who were made to ovulate later by ethinyl E[2].

Conclusions: The short follicular phase per se reduces fecundity.

Journal Title
Clinical and experimental obstetrico & gynecology (Clin. exp. obstet. gynecol.) ISSN 0390-6663 Clinical and experimental obstetrics and gynecology

Source
2003, vol. 30, no4, pp. 195-196 [2 page(s) (article)]

Full article: http://cat.inist.fr/?aModele=afficheN&cpsidt=15335930


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Catherine

About Catherine: I am mom to three grown sons, two grandchildren and two rescue dogs. After years of raising my boys as a single mom, I remarried a wonderful man who had never had a child of his own. Unexpectedly, I found myself pregnant at 49!
Sadly we lost that precious baby at 8 weeks, and decided to try again. Five more losses, turned down for donor egg, foster care and adoption due to my age and losses - we have accepted that there will be no more babies in our house.

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