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Concern over DNA link to fertility risk

Catherine McDiarmid-Watt | Friday, September 26, 2008 | 0 comments

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new research claims antidepressants could damage sperm and risk infertilityA SHEFFIELD fertility expert says new research which claims millions of men who take antidepressants could damage their sperm and risk infertility is 'of concern.'

The findings suggest that commonly described drugs for depression can break up DNA in sperm.

Outwardly the sperm may appear normal in numbers, shape and swimming ability. But similar levels of DNA fragmentation in sperm are said to have led to fertility and pregnancy problems.

For couples undergoing In-Vitro Fertilisation (IVF) treatment, fewer embryos form when the man's sperm has damaged DNA, says the Cornell Medical Center in New York City.

Dr Allan Pacey, senior lecturer in andrology at the University of Sheffield, said: "The apparent increase in sperm DNA damage is alarming, although the level at which we think the damage becomes clinically significant is controversial to many scientists.

"It is a shame that the authors appear not to have conducted a randomised controlled trial which would be the most scientific way to investigate the drugs effects, but the results are of concern and need to be investigated."


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About Catherine: I am mom to three grown sons, two grandchildren and two rescue dogs. After years of raising my boys as a single mom, I remarried a wonderful man who had never had a child of his own. Unexpectedly, I found myself pregnant at 49!
Sadly we lost that precious baby at 8 weeks, and decided to try again. Five more losses, turned down for donor egg, foster care and adoption due to my age and losses - we have accepted that there will be no more babies in our house.

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