Amazon.com lists over 11,000 items under the search term "fertility"

IVF culture oxygen levels 'high, limit embryo quality'

Catherine McDiarmid-Watt | Tuesday, September 09, 2008 | 0 comments

Picture by infertility_ivf_pcos
IVF culture oxygen levels high, limit embryo qualityComparing the effects of different oxygen concentrations in embryo culture medium on the development of embryos in vitro.

MedWire News: The concentrations of oxygen commonly used to culture embryos in vitro limit blastocyst development, say scientists who recommend an alternative method for increasing yield.

In normal pregnancy, embryos are exposed to oxygen concentrations of 2-8 percent but in vitro embryo cultures are typically maintained at atmospheric oxygen levels of 20 percent.

The small amount of available research indicates that atmospheric oxygen levels inhibit normal embryo development.

To investigate further, Mustafa Bahceci (Bahceci Women's Health Care Center, Istanbul, Turkey) and co-workers randomly allocated sibling oocytes to culture conditions that mimicked the physiological norm (6 percent carbon dioxide, 5 percent oxygen, and 89 percent nitrogen) for 6 days from insemination, or to atmospheric oxygen levels (20 percent) and the same carbon dioxide and nitrogen levels for 3 days after insemination, before switching to physiologically normal conditions.

Exposing embryos to a physiological-normal gaseous environment improved blastocyst yield at day 6 after insemination from an average of 42.4 to 47.7 and significantly improved overall embryo quality.

Bahceci and colleagues say: "Increased blastocyst yield with better quality may cause improved pregnancy, implantation, and delivery rates in a physiologic oxygen environment."

They conclude that modifying the oxygen concentrations used in IVF cultures might improve pregnancy rates after IVF.

(c) 2008 Current Medicine Group Ltd, a part of Springer Science+Business Media
Source: Fertility and Sterility 2008; Advance online publication



Life Begins...
Miscarriage stories of loss, hope & help
http://born2luv.blogspot.com/

Stories of Pregnancy & Birth over 44y
- Daily blog of hope & inspiration!
http://pregnancyover44y.blogspot.com/

4,750 Stories of Pregnancy & Birth over 44y
Daily blog of hope & inspiration!
http://pregnancyover44y.blogspot.com/


Recent Keyword Searches: can you get pregnant naturally over forty , fsh 26, uk repreductive clinics older women, get pregnant after 45, improve egg quality





Category: , ,

Catherine

About Catherine: I am mom to three grown sons, two grandchildren and two rescue dogs. After years of raising my boys as a single mom, I remarried a wonderful man who had never had a child of his own. Unexpectedly, I found myself pregnant at 49!
Sadly we lost that precious baby at 8 weeks, and decided to try again. Five more losses, turned down for donor egg, foster care and adoption due to my age and losses - we have accepted that there will be no more babies in our house.

Find Catherine on Google+ - Circle us on Google+ - Join us on Facebook - Follow us on Twitter

0 comments

WE LOVE COMMENTS!
Don't just sit there, reading this story or article - say something! Do you believe it? Do you think it is impossible? Do you wish it was you? Do you have a story to share (it might get published!)

NOTE: Comments are moderated - just to stop the spambots - and so may take up to a few hours to be approved.

Catherine reserves the right to review, edit, refuse or delete any comment.

Popular Posts