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Furthermore, the study would determine if delaying the maturation of the follicle by the use of ethinyl estradiol could improve the pregnancy rate.
Methods: The clinical and viable pregnancy rates of 32 infertile patients were matched to 32 similar controls who ovulated at or past day 11.
After 2-3 cycles of demonstrating ovulation before day 11 some patients were treated with ethinyl E[2], 20 mcg daily, from day 2 of the cycle until ovulation.
Results: Clinical and viable pregnancy rates for the normal ovulators (84.4%, 59.3%) were significantly higher than the rates for early ovulators (21.8%, 9.3%).
However, the pregnancy rates were 83.3% and 66.7% for the subset of early ovulators who were made to ovulate later by ethinyl E[2].
Conclusions: The short follicular phase per se reduces fecundity.
Journal Title
Clinical and experimental obstetrico and gynecology (Clin. exp. obstet. gynecol.) ISSN 0390-6663 Clinical and experimental obstetrics and gynecology
Source
2003, vol. 30, no4, pp. 195-196 [2 page(s) (article)]
Full article: Effect of short follicular phase with follicular maturity on conception outcome
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Paperback: 512 pagesClick to order/for more info: Taking Charge of Your Fertility
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